| Gene Information | |
|---|---|
| Gene Name | FAM171A1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 890 |
| Protein Names | Protein FAM171A1 (Astroprincin) (APCN) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000148468 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q5VUB5 |
| Gene Card | FAM171A1 |
| Uniprot ID | Q5VUB5 |
| Pfam | PF10577 |
| In ASD | no |
| Allosteric Prediction | no (-1.000120221) |
| Ortholog in Animals | Alpaca_ FAM171A1 ( ortholog_one2one ) Dog_ FAM171A1 ( ortholog_one2one ) GuineaPig_ FAM171A1 ( ortholog_one2one ) Macaque_ FAM171A1 ( ortholog_one2one ) Mouse_ Fam171a1 ( ortholog_one2one ) Pig_ FAM171A1 ( ortholog_one2one ) Rat_ Fam171a1 ( ortholog_one2one ) Rabbit_ FAM171A1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | FAM171A2, FAM171B |
| Tissue | NA |
| Tissue Specificity | Expressed in heart, brain, liver, skeletal muscle, kidney and pancreas (PubMed:30312582). In brain, expressed by glia, pyramidal neurons and astrocytes (at protein level) (PubMed:30312582). Highly expressed in placental trophoblasts (PubMed:30312582). {ECO:0000269|PubMed:30312582}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs3814165 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:30312582}; Single-pass type I membrane protein {ECO:0000305|PubMed:30312582}. |
| Mouse PG classification | NA |
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