| Gene Information | |
|---|---|
| Gene Name | FAM168B |
| Organism | Homo sapiens (Human) |
| Gene Length | 195 |
| Protein Names | Myelin-associated neurite-outgrowth inhibitor (Mani) (p20) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000152102 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | A1KXE4 |
| Gene Card | FAM168B |
| Uniprot ID | A1KXE4 |
| Pfam | PF14944 |
| In ASD | no |
| Allosteric Prediction | no (-1.19777216) |
| Ortholog in Animals | Alpaca_ FAM168B ( ortholog_one2one ) Dog_ FAM168B ( ortholog_one2one ) GuineaPig_ FAM168B ( ortholog_one2one ) Macaque_ FAM168B ( ortholog_one2one ) Mouse_ Fam168b ( ortholog_one2one ) Pig_ FAM168B ( ortholog_one2one ) Rat_ Fam168b ( ortholog_one2one ) Rabbit_ FAM168B ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | FAM168A |
| Tissue | NA |
| Tissue Specificity | Expressed in the brain, within neuronal axonal fibers and associated with myelin sheets (at protein level). Expression tends to be lower in the brain of Alzheimer disease patients compared to healthy individuals (at protein level). {ECO:0000269|PubMed:20716133}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:D4AEP3}. Cell membrane {ECO:0000250|UniProtKB:Q80XQ8}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q80XQ8}. Cell projection, axon {ECO:0000250|UniProtKB:Q80XQ8}. Note=Expressed in neuronal cell bodies and axonal fibers. {ECO:0000250|UniProtKB:Q80XQ8}. |
| Mouse PG classification | NA |
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