| Gene Information | |
|---|---|
| Gene Name | EIF2A |
| Organism | Homo sapiens (Human) |
| Gene Length | 585 |
| Protein Names | Eukaryotic translation initiation factor 2A (eIF-2A) (65 kDa eukaryotic translation initiation factor 2A) [Cleaved into: Eukaryotic translation initiation factor 2A, N-terminally processed] |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 244 ( ENSG00000144895 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9BY44 |
| Gene Card | EIF2A |
| Uniprot ID | Q9BY44 |
| Pfam | PF08662 |
| In ASD | no |
| Allosteric Prediction | no (-0.055170105) |
| Ortholog in Animals | Alpaca_ EIF2A ( ortholog_one2one ) Dog_ EIF2A ( ortholog_one2one ) GuineaPig_ EIF2A ( ortholog_one2one ) Macaque_ EIF2A ( ortholog_one2one ) Mouse_ Eif2a ( ortholog_one2one ) Pig_ EIF2A ( ortholog_one2one ) Rat_ Eif2a ( ortholog_one2one ) Rabbit_ EIF2A ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed. Expressed at higher level in pancreas, heart, brain and placenta. {ECO:0000269|PubMed:12133843}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001779(Rat);0.015789(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 8DYS (X-ray 1.80A ) |
| DBSNP | rs1132979 rs17850813 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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