| Gene Information | |
|---|---|
| Gene Name | FAM150B |
| Organism | Homo sapiens (Human) |
| Gene Length | 152 |
| Protein Names | ALK and LTK ligand 2 (Augmentor alpha) (AUG-alpha) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q6UX46 |
| Gene Card | ALKAL2 |
| Uniprot ID | Q6UX46 |
| Pfam | PF15129 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed with highest levels in adrenal gland and modest levels in pancreas, testis and uterus. {ECO:0000269|PubMed:25331893}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7LS0 (X-ray 3.05A ) 7MZX (NMR - ) 7N00 (EM 2.27A ) 7NWZ (X-ray 4.17A ) |
| DBSNP | NA |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:30061385}. Cell membrane {ECO:0000269|PubMed:34819673}. Note=Following interaction with receptor tyrosine kinase ALK, associates with the cell membrane, membrane-binding is required to activate ALK. {ECO:0000269|PubMed:34819673}. |
| Mouse PG classification | NA |
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