| Gene Information | |
|---|---|
| Gene Name | SYBU |
| Organism | Homo sapiens (Human) |
| Gene Length | 663 |
| Protein Names | Syntabulin (Golgi-localized syntaphilin-related protein) (Syntaxin-1-binding protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000147642 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9NX95 |
| Gene Card | SYBU |
| Uniprot ID | Q9NX95 |
| Pfam | PF15290 |
| In ASD | no |
| Allosteric Prediction | no (-0.76754174) |
| Ortholog in Animals | Alpaca_ SYBU ( ortholog_one2one ) Dog_ SYBU ( ortholog_one2one ) GuineaPig_ SYBU ( ortholog_one2one ) Macaque_ SYBU ( ortholog_one2one ) Mouse_ Sybu ( ortholog_one2one ) Pig_ SYBU ( ortholog_one2one ) Rat_ Sybu ( ortholog_one2one ) Rabbit_ SYBU ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SNPH |
| Tissue | NA |
| Tissue Specificity | Isoform 3, isoform 4 and isoform 5 are expressed in HeLa cell line (at protein level). Isoform 3 is expressed in fetal and adult brain. Isoform 4 is expressed in numerous fetal tissues (brain, kidney, liver, lung, and thymus) and in adult brain, kidney, liver, lung, pancreas, colon, prostate, small intestine, testis and thymus. Isoform 5 is expressed in fetal brain, brain and small intestine. {ECO:0000269|PubMed:15656992}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | [Isoform 1]: Cytoplasm, cytoskeleton. Cytoplasmic vesicle. Note=Colocalizes with syntaxin vesicles along microtubules in neuronal processes.; [Isoform 3]: Golgi apparatus membrane; Single-pass membrane protein.; [Isoform 4]: Golgi apparatus membrane; Single-pass membrane protein.; [Isoform 5]: Golgi apparatus membrane; Single-pass membrane protein. |
| Mouse PG classification | NA |
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