| Gene Information | |
|---|---|
| Gene Name | ORAI3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 295 |
| Protein Names | Protein orai-3 (Transmembrane protein 142C) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 244 ( ENSG00000175938 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9BRQ5 |
| Gene Card | ORAI3 |
| Uniprot ID | Q9BRQ5 |
| Pfam | PF07856 |
| In ASD | no |
| Allosteric Prediction | no (-0.295404463) |
| Ortholog in Animals | Alpaca_ ORAI3 ( ortholog_one2one ) Dog_ FBXL19 ( ortholog_one2one ) GuineaPig_ ORAI3 ( ortholog_one2one ) Macaque_ ORAI3 ( ortholog_one2one ) Mouse_ Orai3 ( ortholog_one2one ) Pig_ ORAI3 ( ortholog_one2one ) Rat_ Orai3 ( ortholog_one2one ) Rabbit_ ORAI3 ( ortholog_one2one ) |
| Ohnologs | ORAI2 |
| Paralogs | ORAI2, ORAI1 |
| Tissue | NA |
| Tissue Specificity | Expressed in both naive and effector T helper cells with higher levels in effector cells. {ECO:0000269|PubMed:20354224}. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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