| Gene Information | |
|---|---|
| Gene Name | FAM122A |
| Organism | Homo sapiens (Human) |
| Gene Length | 287 |
| Protein Names | PPP2R1A-PPP2R2A-interacting phosphatase regulator 1 (PABIR family member 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q96E09 |
| Gene Card | PABIR1 |
| Uniprot ID | Q96E09 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);0.04(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:33108758}. Cytoplasm {ECO:0000269|PubMed:33108758}. Note=The CHEK1-mediated Ser-37 phosphorylated form is sequestered by 14-3-3 proteins in the cytoplasm and fails to translocate to the nucleus, where it otherwise inhibits serine/threonine-protein phosphatase 2A. {ECO:0000269|PubMed:33108758}. |
| Mouse PG classification | NA |
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