| Gene Information | |
|---|---|
| Gene Name | ROM1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 351 |
| Protein Names | Rod outer segment membrane protein 1 (ROSP1) (Tetraspanin-23) (Tspan-23) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000149489 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q03395 |
| Gene Card | ROM1 |
| Uniprot ID | Q03395 |
| Pfam | PF00335 |
| In ASD | no |
| Allosteric Prediction | no (-0.69021023) |
| Ortholog in Animals | Alpaca_ ROM1 ( ortholog_one2many ) Dog_ ROM1 ( ortholog_one2one ) GuineaPig_ ROM1 ( ortholog_one2one ) Macaque_ ROM1 ( ortholog_one2one ) Mouse_ Rom1 ( ortholog_one2one ) Pig_ ROM1 ( ortholog_one2one ) Rat_ Rom1 ( ortholog_one2one ) Rabbit_ ROM1 ( ortholog_one2one ) |
| Ohnologs | PRPH2 |
| Paralogs | TSPAN12, CD63, TSPAN10, CD9, TSPAN6, TSPAN5, CD37, CD151, TSPAN4, TSPAN1, TSPAN31, UPK1A, TSPAN17, TSPAN11, TSPAN32, TSPAN8, TSPAN13, TSPAN2, CD53, TSPAN9, TSPAN18, CD81, CD82, TSPAN16, TSPAN19, TSPAN7, UPK1B, TSPAN3, TSPAN14, TSPAN15, PRPH2, TSPAN33 |
| Tissue | pineal.gland |
| Tissue Specificity | Retina photoreceptors (at protein level) (PubMed:1610568, PubMed:8504299). In rim region of ROS disks (PubMed:1610568). {ECO:0000269|PubMed:1610568, ECO:0000269|PubMed:8504299}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs143166696 rs199757012 rs747140028 rs146358003 rs1799959 rs150168119 rs767877192 rs200272942 rs137950927 |
| Subcellular location [CC] | Photoreceptor inner segment membrane {ECO:0000250|UniProtKB:P32958, ECO:0000305|PubMed:1610568}; Multi-pass membrane protein {ECO:0000255}. Photoreceptor outer segment membrane {ECO:0000269|PubMed:1610568}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | HPG |
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