| Gene Information | |
|---|---|
| Gene Name | LYPD8 |
| Organism | Homo sapiens (Human) |
| Gene Length | 237 |
| Protein Names | Ly6/PLAUR domain-containing protein 8 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 78 ( ENSG00000259823 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q6UX82 |
| Gene Card | LYPD8 |
| Uniprot ID | Q6UX82 |
| Pfam | PF00021 |
| In ASD | no |
| Allosteric Prediction | no (-1.234648346) |
| Ortholog in Animals | Alpaca_ LYPD8 ( ortholog_one2one ) Dog_ LYPD8 ( ortholog_one2one ) Macaque_ LYPD8 ( ortholog_one2one ) Mouse_ Lypd8 ( ortholog_one2one ) Pig_ LYPD8 ( ortholog_one2one ) Rat_ Lypd8 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PINLYP |
| Tissue | colon, rectum, transverse.colon |
| Tissue Specificity | Expressed in the large intestine. Preferentially expressed on the epithelial layer exposed to the lumen (at protein level). {ECO:0000269|PubMed:27027293}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane {ECO:0000250|UniProtKB:Q9D7S0}; Lipid-anchor, GPI-anchor {ECO:0000250|UniProtKB:Q9D7S0}. Secreted {ECO:0000250|UniProtKB:Q9D7S0}. Note=Secreted into the lumen of the colon following cleavage of the GPI-anchor. {ECO:0000250|UniProtKB:Q9D7S0}. |
| Mouse PG classification | NA |
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