| Gene Information | |
|---|---|
| Gene Name | FAM109A |
| Organism | Homo sapiens (Human) |
| Gene Length | 249 |
| Protein Names | Sesquipedalian-1 (Ses1) (27 kDa inositol polyphosphate phosphatase-interacting protein A) (IPIP27A) (PH domain-containing endocytic trafficking adaptor 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q8N4B1 |
| Gene Card | PHETA1 |
| Uniprot ID | Q8N4B1 |
| Pfam | PF00169 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3QIS (X-ray 2.30A ) |
| DBSNP | NA |
| Subcellular location [CC] | Early endosome {ECO:0000269|PubMed:21233288}. Recycling endosome {ECO:0000269|PubMed:21233288}. Golgi apparatus, trans-Golgi network {ECO:0000269|PubMed:21233288}. Cytoplasmic vesicle, clathrin-coated vesicle {ECO:0000269|PubMed:21233288}. Note=Interaction with OCRL may be crucial for targeting to endosome and to the trans-Golgi network. Also found on macropinosomes. Not detected in late endosomes, nor in lysosomes. {ECO:0000269|PubMed:20133602, ECO:0000269|PubMed:21233288}. |
| Mouse PG classification | NA |
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