| Gene Information | |
|---|---|
| Gene Name | EHM2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 900 |
| Protein Names | Band 4.1-like protein 4B (Erythrocyte membrane protein band 4.1-like 4B) (FERM-containing protein CG1) (Protein EHM2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9H329 |
| Gene Card | EPB41L4B |
| Uniprot ID | Q9H329 |
| Pfam | PF08736; PF09380; PF00373; PF09379 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed at higher levels in acute wounds than chronic wounds with increased expression in healing wounds, especially at the leading wound edge (PubMed:23664528). Isoform 1 is highly expressed in brain. Isoform 2 is highly expressed in testis with lower levels in prostate and breast (PubMed:14521927). {ECO:0000269|PubMed:14521927, ECO:0000269|PubMed:23664528}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs3750450 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:22006950}. Cell junction, tight junction {ECO:0000269|PubMed:22006950}. Note=Accumulates along apical cell-cell boundaries and is also detected in the cytoplasm in a punctate manner. {ECO:0000269|PubMed:22006950}. |
| Mouse PG classification | NA |
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