| Gene Information | |
|---|---|
| Gene Name | FANCL |
| Organism | Homo sapiens (Human) |
| Gene Length | 375 |
| Protein Names | E3 ubiquitin-protein ligase FANCL (EC 2.3.2.27) (Fanconi anemia group L protein) (Fanconi anemia-associated polypeptide of 43 kDa) (FAAP43) (RING-type E3 ubiquitin transferase FANCL) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000115392 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9NW38 |
| Gene Card | FANCL |
| Uniprot ID | Q9NW38 |
| Pfam | PF11793; PF09765; PF18890; PF18891 |
| In ASD | no |
| Allosteric Prediction | no (-0.618949536) |
| Ortholog in Animals | Alpaca_ FANCL ( ortholog_one2one ) Dog_ FANCL ( ortholog_one2one ) GuineaPig_ FANCL ( ortholog_one2one ) Macaque_ FANCL ( ortholog_one2one ) Mouse_ Fancl ( ortholog_one2one ) Pig_ FANCL ( ortholog_one2one ) Rat_ Fancl ( ortholog_one2one ) Rabbit_ FANCL ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.029915(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3ZQS (X-ray 2.00A ) 4CCG (X-ray 2.40A ) 7KZP (EM 3.10A ) 7KZQ (EM 4.20A ) 7KZR (EM 4.20A ) 7KZS (EM 4.20A ) 7KZT (EM 4.20A ) 7KZV (EM 4.20A ) |
| DBSNP | rs36059257 |
| Subcellular location [CC] | Cytoplasm. Nucleus. |
| Mouse PG classification | LPG |
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