| Gene Information | |
|---|---|
| Gene Name | SPC24 |
| Organism | Homo sapiens (Human) |
| Gene Length | 197 |
| Protein Names | Kinetochore protein Spc24 (hSpc24) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 886 ( ENSG00000161888 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q8NBT2 |
| Gene Card | SPC24 |
| Uniprot ID | Q8NBT2 |
| Pfam | PF08286 |
| In ASD | no |
| Allosteric Prediction | no (-0.231189726) |
| Ortholog in Animals | Alpaca_ SPC24 ( ortholog_one2one ) Dog_ SPC24 ( ortholog_one2one ) Macaque_ SPC24 ( ortholog_one2one ) Mouse_ Spc24 ( ortholog_one2one ) Pig_ SPC24 ( ortholog_one2one ) Rat_ Spc24 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.155546(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2VE7 (X-ray 2.88A ) 3IZ0 (EM - ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:14738735, ECO:0000269|PubMed:15561729, ECO:0000269|PubMed:15961401, ECO:0000269|PubMed:15964272}. Chromosome, centromere, kinetochore {ECO:0000269|PubMed:14738735, ECO:0000269|PubMed:15561729, ECO:0000269|PubMed:15961401, ECO:0000269|PubMed:15964272}. Note=Localizes to kinetochores from late prophase to anaphase. Localizes specifically to the outer plate of the kinetochore. {ECO:0000269|PubMed:14738735}. |
| Mouse PG classification | NA |
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