| Gene Information | |
|---|---|
| Gene Name | FADS3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 445 |
| Protein Names | Fatty acid desaturase 3 (EC 1.14.19.-) (Delta(13) fatty acid desaturase) (Delta(13) desaturase) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1292 ( ENSG00000221968 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q9Y5Q0 |
| Gene Card | FADS3 |
| Uniprot ID | Q9Y5Q0 |
| Pfam | PF00173; PF00487 |
| In ASD | no |
| Allosteric Prediction | no (-0.82856413) |
| Ortholog in Animals | Alpaca_ FADS3 ( ortholog_one2one ) Dog_ FADS3 ( ortholog_one2one ) GuineaPig_ FADS3 ( ortholog_one2one ) Macaque_ FADS3 ( ortholog_one2one ) Mouse_ Fads3 ( ortholog_one2one ) Pig_ FADS3 ( ortholog_one2one ) Rat_ Fads3 ( ortholog_one2one ) Rabbit_ FADS3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | FADS2, FADS1, FADS6 |
| Tissue | NA |
| Tissue Specificity | Highly expressed in various organs and tissues including liver, kidney, brain, lung, pancreas, testis, ovary and skeletal muscle (at protein level). {ECO:0000269|PubMed:19752397}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs35479241 rs34511441 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:31916624}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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