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Gene Information
Gene Name
F8VWF
Organism
Homo sapiens (Human)
Gene Length
2813
Protein Names
von Willebrand factor (vWF) [Cleaved into: von Willebrand antigen 2 (von Willebrand antigen II)]
Target Name
NA
Target Type
NA
Gene Age
NA
Evolutionary Stage
NA
AlphaFoldDB
NA
Gene Card
VWF
Uniprot ID
P04275
Pfam
PF08742; PF01826; PF00092; PF16164; PF00093; PF00094
In ASD
yes
Allosteric Prediction
NA
Ortholog in Animals
NA
Ohnologs
NA
Paralogs
NA
Tissue
NA
Tissue Specificity
Plasma.
Pharmacological Animal Models
NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.04(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB
1AO3
(X-ray
2.20A
)
1ATZ
(X-ray
1.80A
)
1AUQ
(X-ray
2.30A
)
1FE8
(X-ray
2.03A
)
1FNS
(X-ray
2.00A
)
1IJB
(X-ray
1.80A
)
1IJK
(X-ray
2.60A
)
1M10
(X-ray
3.10A
)
1OAK
(X-ray
2.20A
)
1SQ0
(X-ray
2.60A
)
1U0N
(X-ray
2.95A
)
1UEX
(X-ray
2.85A
)
2ADF
(X-ray
1.90A
)
2MHP
(NMR
-
)
2MHQ
(NMR
-
)
3GXB
(X-ray
1.90A
)
3HXO
(X-ray
2.40A
)
3HXQ
(X-ray
2.69A
)
3PPV
(X-ray
1.90A
)
3PPW
(X-ray
1.90A
)
3PPX
(X-ray
1.91A
)
3PPY
(X-ray
2.00A
)
3ZQK
(X-ray
1.70A
)
4C29
(X-ray
2.20A
)
4C2A
(X-ray
2.08A
)
4C2B
(X-ray
2.80A
)
4DMU
(X-ray
2.80A
)
4NT5
(X-ray
3.28A
)
5BV8
(X-ray
1.59A
)
6FWN
(NMR
-
)
6N29
(X-ray
2.50A
)
7EOW
(X-ray
1.60A
)
7F49
(X-ray
2.09A
)
7KWO
(EM
2.90A
)
7P4N
(NMR
-
)
7PMV
(EM
3.70A
)
7PNF
(EM
4.35A
)
7ZWH
(EM
3.20A
)
8D3C
(EM
3.10A
)
8D3D
(EM
3.20A
)
DBSNP
rs61753997
rs1800387
rs62643626
rs1800377
rs1800378
rs61754010
rs61754011
rs2228317
rs61748476
rs1063856
rs61748477
rs121964894
rs216321
rs41276738
rs11064002
rs61748497
rs61748511
rs61749370
rs61749371
rs63524161
rs61749372
rs61749384
rs61749387
rs61749392
rs61749393
rs61749397
rs372028373
rs61749398
rs61749403
rs61750071
rs61750072
rs216311
rs1800382
rs61750088
rs61750089
rs1800383
rs61750101
rs267607342
rs1800385
rs1800386
rs61750117
rs61750577
rs61750117
rs61750579
rs61750580
rs61750581
rs61750584
rs61750588
rs61750590
rs61750596
rs61750615
rs34230288
rs2229446
rs61750630
rs61751298
rs7962217
rs61751305
rs61751310
Subcellular location [CC]
Secreted {ECO:0000269|PubMed:10961880}. Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:10961880}. Note=Localized to storage granules.
Mouse PG classification
NA
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