| Gene Information | |
|---|---|
| Gene Name | ARAF |
| Organism | Homo sapiens (Human) |
| Gene Length | 606 |
| Protein Names | Serine/threonine-protein kinase A-Raf (EC 2.7.11.1) (Proto-oncogene A-Raf) (Proto-oncogene A-Raf-1) (Proto-oncogene Pks) |
| Target Name | serine/threonine-protein kinase a-raf |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000078061 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P10398 |
| Gene Card | ARAF |
| Uniprot ID | P10398 |
| Pfam | PF00130; PF07714; PF02196 |
| In ASD | no |
| Allosteric Prediction | yes (0.692452857) |
| Ortholog in Animals | Alpaca_ ARAF ( ortholog_one2one ) Dog_ ARAF ( ortholog_one2one ) GuineaPig_ ARAF ( ortholog_one2one ) Macaque_ ARAF ( ortholog_one2one ) Mouse_ Araf ( ortholog_one2one ) Pig_ ARAF ( ortholog_one2one ) Rat_ Araf ( ortholog_one2one ) Rabbit_ ARAF ( ortholog_one2one ) |
| Ohnologs | RAF1, BRAF |
| Paralogs | LIMK2, RIPK1, LRRK2, TNNI3K, TESK2, KSR2, MAP3K10, RIPK2, MOS, MAP3K9, MLKL, MAP3K20, TESK1, MAP3K13, BRAF, ILK, MAP3K11, RAF1, MAP3K12, MAP3K21, LIMK1, KSR1, RIPK3 |
| Tissue | NA |
| Tissue Specificity | Predominantly in urogenital tissues. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1WXM (NMR - ) 2MSE (NMR - ) |
| DBSNP | rs56197559 rs55852926 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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