Gene Information
Gene NameF1AA
OrganismHomo sapiens (Human)
Gene Length627
Protein NamesProtein fem-1 homolog B (FEM1b) (FEM1-beta) (Fem-1-like death receptor-binding protein alpha) (Fem-1-like in apoptotic pathway protein alpha) (F1A-alpha)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ9UK73
Gene CardFEM1B
Uniprot IDQ9UK73
PfamPF00023; PF12796
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityWidely expressed (PubMed:10542291). Highly expressed in testis (PubMed:10542291). Weakly expressed in other tissues (PubMed:10542291). {ECO:0000269|PubMed:10542291}.
Pharmacological Animal ModelsNULL(Chimpanzee);0.001000(Mouse);NULL(Rat);0.018182(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 6LBF  (X-ray  3.25A  7CNG  (X-ray  3.49A  7EL6  (X-ray  2.80A 
DBSNP NA 
Subcellular location [CC]Cytoplasm {ECO:0000269|PubMed:19330022, ECO:0000269|PubMed:24076122}. Nucleus {ECO:0000269|PubMed:19330022}. Note=In the nucleus, the protein level increased slightly after camptothecin (CPT) treatment (PubMed:19330022). Associated with chromatin (PubMed:19330022). {ECO:0000269|PubMed:19330022}.
Mouse PG classificationNA
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