| Gene Information | |
|---|---|
| Gene Name | F13B |
| Organism | Homo sapiens (Human) |
| Gene Length | 661 |
| Protein Names | Coagulation factor XIII B chain (Fibrin-stabilizing factor B subunit) (Protein-glutamine gamma-glutamyltransferase B chain) (Transglutaminase B chain) |
| Target Name | coagulation factor xiii |
| Target Type | Clinical trial target |
| Gene Age | 680 ( ENSG00000143278 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | P05160 |
| Gene Card | F13B |
| Uniprot ID | P05160 |
| Pfam | PF00084 |
| In ASD | no |
| Allosteric Prediction | yes (0.456993683) |
| Ortholog in Animals | Alpaca_ F13B ( ortholog_one2one ) Dog_ F13B ( ortholog_one2one ) Macaque_ F13B ( ortholog_one2one ) Mouse_ F13b ( ortholog_one2one ) Pig_ F13B ( ortholog_one2one ) Rat_ F13b ( ortholog_one2one ) Rabbit_ F13B ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CR1L, SUSD3, SELP, SEZ6L2, CFHR2, CFHR1, CSMD1, APOH, SELE, SRPX, SVEP1, SEZ6, C8A, CD55, CSMD2, PAPPA2, SUSD6, C4BPA, C9, CR1, PAPPA, SELL, CFB, CD46, C4BPB, CR2, C7, CSMD3, CFHR3, CFH, SEZ6L, CFHR4, CFHR5, SRPX2, C8B, PRF1, SUSD4, C6, C2 |
| Tissue | liver |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1232302447 rs6002 rs753009140 rs6003 rs757094432 rs145637157 rs778826479 rs17514281 rs5999 rs5991 rs121913075 rs17549671 rs6001 rs6000 |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:26247044, ECO:0000269|PubMed:4405643}. |
| Mouse PG classification | NA |
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