| Gene Information | |
|---|---|
| Gene Name | ITGA9 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1035 |
| Protein Names | Integrin alpha-9 (Integrin alpha-RLC) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000144668 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q13797 |
| Gene Card | ITGA9 |
| Uniprot ID | Q13797 |
| Pfam | PF01839; PF08441 |
| In ASD | no |
| Allosteric Prediction | yes (0.128846531) |
| Ortholog in Animals | Alpaca_ ITGA9 ( ortholog_one2one ) Dog_ ITGA9 ( ortholog_one2one ) GuineaPig_ ITGA9 ( ortholog_one2one ) Macaque_ ITGA9 ( ortholog_one2one ) Mouse_ Itga9 ( ortholog_one2one ) Pig_ ITGA9 ( ortholog_one2one ) Rat_ Itga9 ( ortholog_one2one ) |
| Ohnologs | ITGA3, ITGA7, ITGA6, ITGA4 |
| Paralogs | ITGA10, ITGA4, ITGAX, ITGAE, ITGA2, ITGAD, ITGA5, ITGA6, ITGAV, ITGA7, ITGA8, ITGAL, ITGA3, ITGA2B, ITGA11, ITGA1, ITGAM |
| Tissue | NA |
| Tissue Specificity | In airway epithelium, in the basal layer of squamous epithelium, and in smooth muscle, skeletal muscle, and hepatocytes. Abundantly expressed in fetal lung and lung cancers. {ECO:0000269|PubMed:8245132, ECO:0000269|PubMed:8290272}. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs267561 rs781472543 |
| Subcellular location [CC] | Membrane {ECO:0000255}; Single-pass type I membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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