| Gene Information | |
|---|---|
| Gene Name | F10 |
| Organism | Homo sapiens (Human) |
| Gene Length | 295 |
| Protein Names | Protein FAM110A |
| Target Name | coagulation factor xa |
| Target Type | Successful target |
| Gene Age | 950 ( ENSG00000126218 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9BQ89 |
| Gene Card | FAM110A |
| Uniprot ID | Q9BQ89 |
| Pfam | PF14160; PF14161 |
| In ASD | no |
| Allosteric Prediction | yes (1.399927456) |
| Ortholog in Animals | Alpaca_ F10 ( ortholog_one2many ) Dog_ F10 ( ortholog_one2one ) GuineaPig_ F10 ( ortholog_one2one ) Macaque_ F10 ( ortholog_one2one ) Mouse_ F10 ( ortholog_one2one ) Pig_ F10 ( ortholog_one2one ) Rat_ F10 ( ortholog_one2one ) Rabbit_ F10 ( ortholog_one2one ) |
| Ohnologs | F9, PRSS3, PROC |
| Paralogs | HGFAC, F7, C1R, KLK10, F9, F12, CFI, CFD, PRSS55, PRSS51, C1S, C1RL, HP, HPR, KLKB1, F11 |
| Tissue | NA |
| Tissue Specificity | Detected in thyroid, lymph node, trachea, adrenal gland, bone marrow, spleen, thymus, prostate, and peripheral blood leukocyte. Detected at lower levels in stomach, testis and spinal cord. {ECO:0000269|PubMed:17499476}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | rs6055290 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:17499476}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:17499476}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000269|PubMed:17499476}. Note=Distributed throughout the cytoplasm during mitosis, accumulating at spindle poles. |
| Mouse PG classification | NA |
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