| Gene Information | |
|---|---|
| Gene Name | EYA4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 639 |
| Protein Names | Eyes absent homolog 4 (EC 3.1.3.48) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000112319 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O95677 |
| Gene Card | EYA4 |
| Uniprot ID | O95677 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-0.461741157) |
| Ortholog in Animals | Alpaca_ EYA4 ( ortholog_one2one ) Dog_ EYA4 ( ortholog_one2one ) GuineaPig_ EYA4 ( ortholog_one2one ) Macaque_ EYA4 ( ortholog_one2one ) Mouse_ Eya4 ( ortholog_one2one ) Pig_ EYA4 ( ortholog_one2one ) Rat_ Eya4 ( ortholog_one2one ) Rabbit_ EYA4 ( ortholog_one2one ) |
| Ohnologs | EYA2, EYA1, EYA3 |
| Paralogs | EYA2, EYA1, EYA3 |
| Tissue | NA |
| Tissue Specificity | Highly expressed in heart and skeletal muscle. {ECO:0000269|PubMed:15735644}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1471362858 rs9493627 rs779172192 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250|UniProtKB:Q99502}. Nucleus {ECO:0000250|UniProtKB:Q99502}. |
| Mouse PG classification | LPG |
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