| Gene Information | |
|---|---|
| Gene Name | EYA3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 573 |
| Protein Names | Eyes absent homolog 3 (EC 3.1.3.48) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000158161 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q99504 |
| Gene Card | EYA3 |
| Uniprot ID | Q99504 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-0.461277695) |
| Ortholog in Animals | Alpaca_ EYA3 ( ortholog_one2one ) Dog_ EYA3 ( ortholog_one2one ) GuineaPig_ EYA3 ( ortholog_one2one ) Macaque_ EYA3 ( ortholog_one2one ) Mouse_ Eya3 ( ortholog_one2one ) Pig_ EYA3 ( ortholog_one2one ) Rat_ Eya3 ( ortholog_one2one ) Rabbit_ EYA3 ( ortholog_one2one ) |
| Ohnologs | EYA2, EYA1, EYA4 |
| Paralogs | EYA2, EYA4, EYA1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000250|UniProtKB:P97480}. Nucleus {ECO:0000269|PubMed:19234442}. Note=Localizes at sites of DNA damage at double-strand breaks (DSBs) (PubMed:19234442). With decreasing efficiency, translocalized to the nucleus by SIX2 and SIX5, and SIX4, respectively (By similarity). {ECO:0000250|UniProtKB:P97480, ECO:0000269|PubMed:19234442}. |
| Mouse PG classification | NA |
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