| Gene Information | |
|---|---|
| Gene Name | EXOSC2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 293 |
| Protein Names | Exosome complex component RRP4 (Exosome component 2) (Ribosomal RNA-processing protein 4) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000130713 ) |
| Evolutionary Stage | Euk_Archaea |
| AlphaFoldDB | Q13868 |
| Gene Card | EXOSC2 |
| Uniprot ID | Q13868 |
| Pfam | PF14382; PF15985 |
| In ASD | no |
| Allosteric Prediction | no (-1.026986394) |
| Ortholog in Animals | Alpaca_ EXOSC2 ( ortholog_one2many ) Dog_ EXOSC2 ( ortholog_one2one ) GuineaPig_ EXOSC2 ( ortholog_one2one ) Macaque_ EXOSC2 ( ortholog_one2one ) Mouse_ Exosc2 ( ortholog_one2one ) Pig_ EXOSC2 ( ortholog_one2one ) Rat_ Exosc2 ( ortholog_one2one ) Rabbit_ EXOSC2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | EXOSC3 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.073872(Rat);0.082821(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2NN6 (X-ray 3.35A ) 6D6Q (EM 3.45A ) 6D6R (EM 3.45A ) 6H25 (EM 3.80A ) |
| DBSNP | rs537467155 rs756204866 |
| Subcellular location [CC] | Cytoplasm. Nucleus, nucleolus. Nucleus. |
| Mouse PG classification | NA |
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