| Gene Information | |
|---|---|
| Gene Name | EXOSC10 |
| Organism | Homo sapiens (Human) |
| Gene Length | 885 |
| Protein Names | Exosome component 10 (EC 3.1.13.-) (Autoantigen PM/Scl 2) (P100 polymyositis-scleroderma overlap syndrome-associated autoantigen) (Polymyositis/scleroderma autoantigen 100 kDa) (PM/Scl-100) (Polymyositis/scleroderma autoantigen 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000171824 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q01780 |
| Gene Card | EXOSC10 |
| Uniprot ID | Q01780 |
| Pfam | PF01612; PF00570; PF08066 |
| In ASD | no |
| Allosteric Prediction | no (-1.036933412) |
| Ortholog in Animals | Alpaca_ EXOSC10 ( ortholog_one2one ) Dog_ EXOSC10 ( ortholog_one2one ) GuineaPig_ EXOSC10 ( ortholog_one2one ) Macaque_ EXOSC10 ( ortholog_one2one ) Mouse_ Exosc10 ( ortholog_one2one ) Pig_ EXOSC10 ( ortholog_one2one ) Rat_ Exosc10 ( ortholog_one2one ) Rabbit_ EXOSC10 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | EXD1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.073213(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2CPR (NMR - ) 3SAF (X-ray 2.50A ) 3SAG (X-ray 2.70A ) 3SAH (X-ray 2.65A ) 6D6Q (EM 3.45A ) 6D6R (EM 3.45A ) 7MQA (EM 2.70A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm. Nucleus, nucleolus. Nucleus. Note=Strongly enriched in the nucleolus and a small amount has been found in cytoplasm supporting the existence of a nucleolar RNA exosome complex form. |
| Mouse PG classification | NA |
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