Gene Information
Gene NameEXOSC1
OrganismHomo sapiens (Human)
Gene Length195
Protein NamesExosome complex component CSL4 (Exosome component 1)
Target NameNA
Target TypeNA
Gene Age680 ( ENSG00000171311 )
Evolutionary StageEukaryota
AlphaFoldDBQ9Y3B2
Gene CardEXOSC1
Uniprot IDQ9Y3B2
PfamPF14382; PF10447
In ASDno
Allosteric Predictionno (-1.521556283)
Ortholog in AnimalsAlpaca_ EXOSC1 ( ortholog_one2one )
Dog_ EXOSC1 ( ortholog_one2one )
GuineaPig_ EXOSC1 ( ortholog_one2one )
Mouse_ Exosc1 ( ortholog_one2one )
Pig_ EXOSC1 ( ortholog_one2one )
Rat_ Exosc1 ( ortholog_one2one )
Rabbit_ EXOSC1 ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityNA
Pharmacological Animal Models0.189405(Chimpanzee);0.138286(Mouse);0.073454(Rat);0.049535(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 2NN6  (X-ray  3.35A  6D6Q  (EM  3.45A  6D6R  (EM  3.45A  6H25  (EM  3.80A 
DBSNP NA 
Subcellular location [CC]Nucleus, nucleolus {ECO:0000269|PubMed:11812149}. Nucleus {ECO:0000305|PubMed:11812149}. Cytoplasm {ECO:0000305|PubMed:11812149}.
Mouse PG classificationNA
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