| Gene Information | |
|---|---|
| Gene Name | EXOC6 |
| Organism | Homo sapiens (Human) |
| Gene Length | 804 |
| Protein Names | Exocyst complex component 6 (Exocyst complex component Sec15A) (SEC15-like protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000138190 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8TAG9 |
| Gene Card | EXOC6 |
| Uniprot ID | Q8TAG9 |
| Pfam | PF04091 |
| In ASD | no |
| Allosteric Prediction | yes (0.068427468) |
| Ortholog in Animals | Alpaca_ EXOC6 ( ortholog_one2one ) Dog_ EXOC6 ( ortholog_one2one ) GuineaPig_ EXOC6 ( ortholog_one2one ) Macaque_ EXOC6 ( ortholog_one2one ) Mouse_ Exoc6 ( ortholog_one2one ) Pig_ EXOC6 ( ortholog_one2one ) Rat_ Exoc6 ( ortholog_one2one ) Rabbit_ EXOC6 ( ortholog_one2one ) |
| Ohnologs | EXOC6B |
| Paralogs | EXOC6B |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.07855(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1326331 rs11187225 rs35647717 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250|UniProtKB:O54923}. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:O54923}. Cell projection, growth cone {ECO:0000250|UniProtKB:O54923}. Midbody, Midbody ring {ECO:0000269|PubMed:16213214}. Note=Perinuclear in undifferentiated cells. Redistributes to growing neurites and growth cones during neuronal differentiation. Colocalizes with CNTRL/centriolin at the midbody ring (PubMed:16213214). {ECO:0000250|UniProtKB:O54923, ECO:0000269|PubMed:16213214}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |