| Gene Information | |
|---|---|
| Gene Name | EXOC2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 924 |
| Protein Names | Exocyst complex component 2 (Exocyst complex component Sec5) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 168 ( ENSG00000112685 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q96KP1 |
| Gene Card | EXOC2 |
| Uniprot ID | Q96KP1 |
| Pfam | PF15469; PF01833 |
| In ASD | no |
| Allosteric Prediction | no (-0.212395532) |
| Ortholog in Animals | Alpaca_ EXOC2 ( ortholog_one2one ) Dog_ EXOC2 ( ortholog_one2one ) GuineaPig_ EXOC2 ( ortholog_one2one ) Macaque_ EXOC2 ( ortholog_one2one ) Mouse_ Exoc2 ( ortholog_one2one ) Pig_ EXOC2 ( ortholog_one2one ) Rat_ Exoc2 ( ortholog_one2one ) Rabbit_ EXOC2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed with highest levels in brain and placenta. {ECO:0000269|PubMed:12459492}. |
| Pharmacological Animal Models | 0.082702(Chimpanzee);0.078874(Mouse);NULL(Rat);0.087280(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs35600069 |
| Subcellular location [CC] | Midbody, Midbody ring {ECO:0000269|PubMed:16213214, ECO:0000269|PubMed:18756269}. Note=Recruitment to the midbody does not require RALA, nor RALB (PubMed:18756269). Colocalizes with CNTRL/centriolin at the midbody ring (PubMed:16213214). {ECO:0000269|PubMed:16213214, ECO:0000269|PubMed:18756269}. |
| Mouse PG classification | NA |
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