| Gene Information | |
|---|---|
| Gene Name | EXO70 |
| Organism | Homo sapiens (Human) |
| Gene Length | 735 |
| Protein Names | Exocyst complex component 7 (Exocyst complex component Exo70) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9UPT5 |
| Gene Card | EXOC7 |
| Uniprot ID | Q9UPT5 |
| Pfam | PF03081 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Abundant in the ventricular zone, the outer subventricular zone and the cortical plate of the fetal cortex. {ECO:0000269|PubMed:32103185}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.045216(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs762553587 |
| Subcellular location [CC] | Cytoplasm, cytosol {ECO:0000250|UniProtKB:O35250}. Cell membrane {ECO:0000250|UniProtKB:O35250}; Peripheral membrane protein {ECO:0000305}. Midbody, Midbody ring {ECO:0000269|PubMed:16213214}. Note=Translocates, as a preformed complex with EXOC3/SEC6 and EXOC4/SEC8, to the plasma membrane in response to insulin through the activation of ARHQ (By similarity). Colocalizes with CNTRL/centriolin at the midbody ring (PubMed:16213214). {ECO:0000250|UniProtKB:O35250, ECO:0000269|PubMed:16213214}. |
| Mouse PG classification | NA |
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