| Gene Information | |
|---|---|
| Gene Name | EWSR1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 656 |
| Protein Names | RNA-binding protein EWS (EWS oncogene) (Ewing sarcoma breakpoint region 1 protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000182944 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q01844 |
| Gene Card | EWSR1 |
| Uniprot ID | Q01844 |
| Pfam | PF00076; PF00641 |
| In ASD | no |
| Allosteric Prediction | no (-0.667847392) |
| Ortholog in Animals | Alpaca_ EWSR1 ( ortholog_one2one ) Dog_ EWSR1 ( ortholog_one2many ) GuineaPig_ EWSR1 ( ortholog_one2one ) Macaque_ EWSR1 ( ortholog_one2one ) Mouse_ Ewsr1 ( ortholog_one2one ) Pig_ EWSR1 ( ortholog_one2one ) Rat_ Ewsr1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | FUS, TAF15 |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2CPE (NMR - ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:16965792}. Cytoplasm {ECO:0000269|PubMed:16965792}. Cell membrane {ECO:0000269|PubMed:16965792}. Note=Relocates from cytoplasm to ribosomes upon PTK2B/FAK2 activation. |
| Mouse PG classification | NA |
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