Gene Information
Gene NameEWI101
OrganismHomo sapiens (Human)
Gene Length1021
Protein NamesImmunoglobulin superfamily member 2 (IgSF2) (Cell surface glycoprotein V7) (Glu-Trp-Ile EWI motif-containing protein 101) (EWI-101) (CD antigen CD101)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ93033
Gene CardCD101
Uniprot IDQ93033
PfamPF07679; PF07686
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityExpressed in lung, thymus and small intestine. Detected in cutaneous dendritic cells, activated T-cells, monocytes and granulocytes as well as with epithelial cells with dendritic morphology. Expressed in some leukemic cells, the CD4(+) CD56(+) blastic tumor cells, as well as in Langerhans cells from LCH (Langerhans cell histiocytosis) patients. {ECO:0000269|PubMed:10692025, ECO:0000269|PubMed:15737213, ECO:0000269|PubMed:7722299, ECO:0000269|PubMed:7722300, ECO:0000269|PubMed:9389317}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs34999087  rs3754112  rs2249265  rs17235766  rs17235773  rs34510762  rs12093834  rs34223095  rs12097758  rs12067543  rs34248572 
Subcellular location [CC]Membrane {ECO:0000305};
Single-pass type I membrane protein {ECO:0000305}.
Mouse PG classificationNA
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