| Gene Information | |
|---|---|
| Gene Name | EVL |
| Organism | Homo sapiens (Human) |
| Gene Length | 416 |
| Protein Names | Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein-like) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000196405 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9UI08 |
| Gene Card | EVL |
| Uniprot ID | Q9UI08 |
| Pfam | PF08776; PF00568 |
| In ASD | no |
| Allosteric Prediction | no (-0.22765873) |
| Ortholog in Animals | Alpaca_ EVL ( ortholog_one2one ) Dog_ EVL ( ortholog_one2one ) GuineaPig_ EVL ( ortholog_one2one ) Macaque_ EVL ( ortholog_one2one ) Mouse_ Evl ( ortholog_one2one ) Pig_ EVL ( ortholog_one2one ) Rat_ Evl ( ortholog_one2one ) |
| Ohnologs | VASP |
| Paralogs | SPRED3, SPRED1, VASP, ENAH, SPRED2 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs367737727 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:P70429}. Cytoplasm, cytoskeleton, stress fiber {ECO:0000250|UniProtKB:P70429}. Cell projection, lamellipodium {ECO:0000250|UniProtKB:P70429}. Note=Targeted to the leading edge of lamellipodia and the distal tip of stress fibers through interaction with a number of proteins. In activated T-cells, localizes to the F-actin collar and the distal tip of microspikes. {ECO:0000250|UniProtKB:P70429}. |
| Mouse PG classification | NA |
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