| Gene Information | |
|---|---|
| Gene Name | ETV4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 484 |
| Protein Names | ETS translocation variant 4 (Adenovirus E1A enhancer-binding protein) (E1A-F) (Polyomavirus enhancer activator 3 homolog) (Protein PEA3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000175832 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P43268 |
| Gene Card | ETV4 |
| Uniprot ID | P43268 |
| Pfam | PF00178; PF04621 |
| In ASD | no |
| Allosteric Prediction | no (-0.586008252) |
| Ortholog in Animals | Alpaca_ ETV4 ( ortholog_one2one ) Dog_ ETV4 ( ortholog_one2one ) GuineaPig_ ETV4 ( ortholog_one2one ) Macaque_ ETV4 ( ortholog_one2one ) Mouse_ Etv4 ( ortholog_one2one ) Pig_ ETV4 ( ortholog_one2one ) Rat_ Etv4 ( ortholog_one2one ) Rabbit_ ETV4 ( ortholog_one2one ) |
| Ohnologs | ETV1 |
| Paralogs | ELK1, ETV6, ERG, ERF, ETV7, ELF4, ELF3, EHF, ETV2, ETV3L, ETS2, FLI1, GABPA, ETV5, ETV1, ELF5, ETV3, ELK3, ETS1, ELF2, SPI1, ELK4, ELF1, SPIB, FEV, SPIC, ERFL, SPDEF |
| Tissue | NA |
| Tissue Specificity | Expressed in keratinocytes. {ECO:0000269|PubMed:31552090}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.1(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4CO8 (X-ray 1.05A ) 4UUV (X-ray 2.80A ) 5ILU (X-ray 1.10A ) |
| DBSNP | rs150119757 rs34260468 |
| Subcellular location [CC] | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00237}. |
| Mouse PG classification | NA |
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