| Gene Information | |
|---|---|
| Gene Name | ETR3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 508 |
| Protein Names | CUGBP Elav-like family member 2 (CELF-2) (Bruno-like protein 3) (CUG triplet repeat RNA-binding protein 2) (CUG-BP2) (CUG-BP- and ETR-3-like factor 2) (ELAV-type RNA-binding protein 3) (ETR-3) (Neuroblastoma apoptosis-related RNA-binding protein) (hNAPOR) (RNA-binding protein BRUNOL-3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | O95319 |
| Gene Card | CELF2 |
| Uniprot ID | O95319 |
| Pfam | PF00076 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in frontal cortex. Isoform 1 is expressed in brain and lung. Isoform 2 is expressed in heart, brain, placenta, lung, liver, kidney, skeletal muscle and pancreas. Isoform 4 is expressed in heart, lung, skeletal muscle, kidney and pancreas. {ECO:0000269|PubMed:10524244, ECO:0000269|PubMed:10893231, ECO:0000269|PubMed:11158314, ECO:0000269|PubMed:11414768, ECO:0000269|PubMed:16862542}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | 2MY7 (NMR - ) 2MY8 (NMR - ) 4LJM (X-ray 3.00A ) 4LMZ (X-ray 2.78A ) 4TLQ (X-ray 2.50A ) 5M8I (NMR - ) |
| DBSNP | rs1050942 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:33131106}. Cytoplasm {ECO:0000250|UniProtKB:Q7T2T1, ECO:0000250|UniProtKB:Q9Z0H4}. Note=Accumulates in the cytoplasm after ionizing radiation (By similarity). Colocalizes with APOBEC1 and A1CF. RNA-binding activity is detected in both nuclear and cytoplasmic compartments. {ECO:0000250}. |
| Mouse PG classification | NA |
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