| Gene Information | |
|---|---|
| Gene Name | EST1B |
| Organism | Homo sapiens (Human) |
| Gene Length | 1016 |
| Protein Names | Nonsense-mediated mRNA decay factor SMG5 (EST1-like protein B) (LPTS-RP1) (LPTS-interacting protein) (SMG-5 homolog) (hSMG-5) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9UPR3 |
| Gene Card | SMG5 |
| Uniprot ID | Q9UPR3 |
| Pfam | PF10374; PF10373; PF13638 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:12699629, ECO:0000269|PubMed:14636577}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2HWY (X-ray 2.75A ) |
| DBSNP | rs17853821 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:14636577}. Nucleus {ECO:0000269|PubMed:14636577}. Note=Predominantly cytoplasmic, and nuclear. Shuttles between nucleus and cytoplasm. Detected in cytoplasmic mRNA decay bodies. |
| Mouse PG classification | NA |
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