| Gene Information | |
|---|---|
| Gene Name | ESO1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 180 |
| Protein Names | Cancer/testis antigen 1 (Autoimmunogenic cancer/testis antigen NY-ESO-1) (Cancer/testis antigen 6.1) (CT6.1) (L antigen family member 2) (LAGE-2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P78358 |
| Gene Card | CTAG1A;CTAG1B |
| Uniprot ID | P78358 |
| Pfam | PF09341 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in testis and ovary and in a wide variety of cancers. Detected in uterine myometrium. Expressed from 18 weeks until birth in human fetal testis. In the adult testis, is strongly expressed in spermatogonia and in primary spermatocytes, but not in post-meiotic cells or in testicular somatic cells (at protein level). {ECO:0000269|PubMed:12065688}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1S9W (X-ray 2.20A ) 2BNQ (X-ray 1.70A ) 2BNR (X-ray 1.90A ) 2F53 (X-ray 2.10A ) 2F54 (X-ray 2.70A ) 2P5E (X-ray 1.89A ) 2P5W (X-ray 2.20A ) 2PYE (X-ray 2.30A ) 3GJF (X-ray 1.90A ) 3HAE (X-ray 2.90A ) 3KLA (X-ray 1.65A ) 6AT5 (X-ray 1.50A ) 6AVF (X-ray 2.03A ) 6AVG (X-ray 2.60A ) 6RP9 (X-ray 3.12A ) 6RPA (X-ray 2.56A ) 6RPB (X-ray 2.50A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:12065688}. |
| Mouse PG classification | NA |
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