| Gene Information | |
|---|---|
| Gene Name | CDK18 |
| Organism | Homo sapiens (Human) |
| Gene Length | 474 |
| Protein Names | Cyclin-dependent kinase 18 (EC 2.7.11.22) (Cell division protein kinase 18) (PCTAIRE-motif protein kinase 3) (Serine/threonine-protein kinase PCTAIRE-3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000117266 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q07002 |
| Gene Card | CDK18 |
| Uniprot ID | Q07002 |
| Pfam | PF00069 |
| In ASD | no |
| Allosteric Prediction | no (-0.920760006) |
| Ortholog in Animals | Alpaca_ CDK18 ( ortholog_one2one ) Dog_ CDK18 ( ortholog_one2one ) GuineaPig_ CDK18 ( ortholog_one2one ) Macaque_ CDK18 ( ortholog_one2one ) Mouse_ Cdk18 ( ortholog_one2one ) Pig_ CDK18 ( ortholog_one2one ) Rat_ Cdk18 ( ortholog_one2one ) |
| Ohnologs | CDK17, CDK16 |
| Paralogs | CDK14, CDKL2, CDK5, CDKL3, CDK7, CDK3, CDK1, CDKL1, CDK19, CDKL5, CDK6, CDK16, CDK15, CDK4, CDKL4, CDK2, CDK20, CDK9, CDK12, CDK8, CDK10, CDK11B, CDK11A, CDK13, CDK17, PRPF4B |
| Tissue | spinal.cord |
| Tissue Specificity | Isoform 2 expression is limited to several subcortical nuclei of the basal gangli and the spinal cord. Isoform 1 is widely expressed. {ECO:0000269|PubMed:15019984}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs35134237 rs4623769 rs17850752 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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