| Gene Information | |
|---|---|
| Gene Name | ESCO1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 840 |
| Protein Names | N-acetyltransferase ESCO1 (EC 2.3.1.-) (CTF7 homolog 1) (Establishment factor-like protein 1) (EFO1) (EFO1p) (hEFO1) (Establishment of cohesion 1 homolog 1) (ECO1 homolog 1) (ESO1 homolog 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000141446 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q5FWF5 |
| Gene Card | ESCO1 |
| Uniprot ID | Q5FWF5 |
| Pfam | PF13880; PF13878 |
| In ASD | no |
| Allosteric Prediction | no (-0.463255373) |
| Ortholog in Animals | Alpaca_ ESCO1 ( ortholog_one2one ) Dog_ ESCO1 ( ortholog_one2one ) Macaque_ ESCO1 ( ortholog_one2one ) Mouse_ Esco1 ( ortholog_one2one ) Pig_ ESCO1 ( ortholog_one2one ) Rat_ Esco1 ( ortholog_one2one ) Rabbit_ ESCO1 ( ortholog_one2one ) |
| Ohnologs | ESCO2 |
| Paralogs | REV1, POLI, POLH, ESCO2, POLK |
| Tissue | NA |
| Tissue Specificity | Widely expressed. Expressed in heart, brain, liver, placenta, lung, kidney and pancreas. Highly expressed in muscle. {ECO:0000269|PubMed:14576321}. |
| Pharmacological Animal Models | 0.054226(Chimpanzee);0.021238(Mouse);0.001000(Rat);0.066667(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | 4MXE (X-ray 2.60A ) 5T53 (X-ray 2.70A ) |
| DBSNP | rs35087820 rs13381941 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:14576321, ECO:0000269|PubMed:15958495}. Chromosome {ECO:0000269|PubMed:15958495}. Note=Nuclear at interphase, associated with chromosomes during mitosis. {ECO:0000269|PubMed:15958495}. |
| Mouse PG classification | NA |
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