| Gene Information | |
|---|---|
| Gene Name | ERRFI1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 462 |
| Protein Names | ERBB receptor feedback inhibitor 1 (Mitogen-inducible gene 6 protein) (MIG-6) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000116285 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9UJM3 |
| Gene Card | ERRFI1 |
| Uniprot ID | Q9UJM3 |
| Pfam | PF09027; PF11555 |
| In ASD | no |
| Allosteric Prediction | yes (0.387198708) |
| Ortholog in Animals | Alpaca_ ERRFI1 ( ortholog_one2one ) Dog_ ERRFI1 ( ortholog_one2one ) GuineaPig_ ERRFI1 ( ortholog_one2one ) Macaque_ ERRFI1 ( ortholog_one2one ) Mouse_ Errfi1 ( ortholog_one2one ) Pig_ ERRFI1 ( ortholog_one2one ) Rat_ Errfi1 ( ortholog_one2one ) Rabbit_ ERRFI1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.04(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2RF9 (X-ray 3.50A ) 2RFD (X-ray 3.60A ) 2RFE (X-ray 2.90A ) 4I21 (X-ray 3.37A ) 4R3P (X-ray 2.90A ) 4R3R (X-ray 3.25A ) 4ZJV (X-ray 2.70A ) |
| DBSNP | rs34781518 rs34974993 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:7641805}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Nucleus {ECO:0000250}. Note=Associated with the plasma membrane of basal skin keratinocytes. Translocates into the nucleus of differentiating suprabasal keratinocytes (By similarity). {ECO:0000250}. |
| Mouse PG classification | NA |
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