Gene Information
Gene NameRAB11B
OrganismHomo sapiens (Human)
Gene Length218
Protein NamesRas-related protein Rab-11B (EC 3.6.5.2) (GTP-binding protein YPT3)
Target NameNA
Target TypeNA
Gene Age1488 ( ENSG00000185236 )
Evolutionary StageEukaryota
AlphaFoldDBQ15907
Gene CardRAB11B
Uniprot IDQ15907
PfamPF00071
In ASDno
Allosteric Predictionno (-0.703480345)
Ortholog in AnimalsGuineaPig_ RAB11B ( ortholog_one2one )
Macaque_ RAB11B ( ortholog_one2one )
Mouse_ Rab11b ( ortholog_one2one )
Rabbit_ RAB11B ( ortholog_one2one )
OhnologsRAB11A
ParalogsRAB14, RAB5C, RAB39A, RAB27B, RAB36, RAB33B, RABL2A, RABL2B, RAB27A, RAB3C, RAB5A, RAB15, RAB40AL, RAB3A, RAB40C, RAB12, RAB8A, RAB17, RAB20, RAB24, RAB44, RAB1A, RAB11A, RAB31, RAB7A, IFT27, RAB29, RAB33A, RAB9B, RAB10, RAB4B, RAB32, RAB4A, RAB19, RAB42, RAB9A, RAB40A, RAB2B, RAB2A, RAB43, RAB18, RAB37, RAB25, RASEF, RAB6D, RAB6C, RAB8B, RAB41, RAB40B, RAB21, RAB39B, RAB28, RAB5B, RAB13, RAB38, RAB3B, RAB34, RAB7B, RAB35, RAB3D, RAB1B, RAB6B, RAB22A, RAB26, RAB23, RAB30, RAB6A, DNAJC27
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 2F9L  (X-ray  1.55A  )  2F9M  (X-ray  1.95A  )  4OJK  (X-ray  2.66A  ) 
DBSNP rs1555690779  rs1555690804 
Subcellular location [CC]Recycling endosome membrane {ECO:0000250|UniProtKB:P46638};
Lipid-anchor {ECO:0000250|UniProtKB:P46638};
Cytoplasmic side {ECO:0000250|UniProtKB:P46638}. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250|UniProtKB:O35509};
Lipid-anchor {ECO:0000250|UniProtKB:O35509};
Cytoplasmic side {ECO:0000250|UniProtKB:O35509}. Cytoplasmic vesicle, phagosome membrane {ECO:0000305|PubMed:21255211};
Lipid-anchor {ECO:0000305|PubMed:21255211};
Cytoplasmic side {ECO:0000305|PubMed:21255211}. Note=Recruited to phagosomes containing S.aureus. {ECO:0000305|PubMed:21255211}.
Mouse PG classificationNA
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