| Gene Information | |
|---|---|
| Gene Name | ERI1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 349 |
| Protein Names | 3'-5' exoribonuclease 1 (EC 3.1.-.-) (3'-5' exonuclease ERI1) (Eri-1 homolog) (Histone mRNA 3'-end-specific exoribonuclease) (Histone mRNA 3'-exonuclease 1) (Protein 3'hExo) (HEXO) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000104626 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q8IV48 |
| Gene Card | ERI1 |
| Uniprot ID | Q8IV48 |
| Pfam | PF00929; PF02037 |
| In ASD | no |
| Allosteric Prediction | no (-1.375452067) |
| Ortholog in Animals | Alpaca_ ERI1 ( ortholog_one2one ) Dog_ ERI1 ( ortholog_one2one ) GuineaPig_ ERI1 ( ortholog_one2one ) Macaque_ ERI1 ( ortholog_one2one ) Mouse_ Eri1 ( ortholog_one2one ) Pig_ ERI1 ( ortholog_one2one ) Rat_ Eri1 ( ortholog_one2one ) Rabbit_ ERI1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ERI3, ERI2 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1W0H (X-ray 1.59A ) 1ZBH (X-ray 3.00A ) 1ZBU (X-ray 3.00A ) 4L8R (X-ray 2.60A ) 4QOZ (X-ray 2.30A ) |
| DBSNP | rs2288672 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:16912046}. Nucleus {ECO:0000269|PubMed:16912046}. Nucleus, nucleolus {ECO:0000269|PubMed:16912046}. |
| Mouse PG classification | NA |
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