| Gene Information | |
|---|---|
| Gene Name | ERGIC2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 377 |
| Protein Names | Endoplasmic reticulum-Golgi intermediate compartment protein 2 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000087502 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q96RQ1 |
| Gene Card | ERGIC2 |
| Uniprot ID | Q96RQ1 |
| Pfam | PF07970; PF13850 |
| In ASD | no |
| Allosteric Prediction | yes (0.040637202) |
| Ortholog in Animals | Alpaca_ ERGIC2 ( ortholog_one2one ) Dog_ ERGIC2 ( ortholog_one2one ) GuineaPig_ ERGIC2 ( ortholog_one2one ) Macaque_ ERGIC2 ( ortholog_one2one ) Mouse_ Ergic2 ( ortholog_one2one ) Pig_ ERGIC2 ( ortholog_one2one ) Rat_ Ergic2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ERGIC3, ERGIC1 |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed. {ECO:0000269|PubMed:11445006}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.057143(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Golgi apparatus, cis-Golgi network membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Cytoplasm. Nucleus. Note=Cycles between the endoplasmic reticulum and the Golgi. According to a report, localizes to the nucleus (PubMed:11445006). Another report shows a partial localization in the nucleus (PubMed:17980171). {ECO:0000269|PubMed:11445006, ECO:0000269|PubMed:17980171}. |
| Mouse PG classification | NA |
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