| Gene Information | |
|---|---|
| Gene Name | ERG |
| Organism | Homo sapiens (Human) |
| Gene Length | 479 |
| Protein Names | Transcriptional regulator ERG (Transforming protein ERG) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000157554 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P11308 |
| Gene Card | ERG |
| Uniprot ID | P11308 |
| Pfam | PF00178; PF02198 |
| In ASD | yes |
| Allosteric Prediction | yes (1.041799709) |
| Ortholog in Animals | Alpaca_ ERG ( ortholog_one2one ) Dog_ ERG ( ortholog_one2one ) GuineaPig_ ERG ( ortholog_one2one ) Macaque_ ERG ( ortholog_one2one ) Mouse_ Erg ( ortholog_one2one ) Pig_ ERG ( ortholog_one2one ) Rat_ Erg ( ortholog_one2one ) Rabbit_ ERG ( ortholog_one2one ) |
| Ohnologs | FLI1 |
| Paralogs | ELK1, ETV6, ERF, ETV4, ETV7, ELF4, ELF3, EHF, ETV2, ETV3L, ETS2, FLI1, GABPA, ETV5, ETV1, ELF5, ETV3, ELK3, ETS1, ELF2, SPI1, ELK4, ELF1, SPIB, FEV, SPIC, ERFL, SPDEF |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1SXE (NMR - ) 4IRG (X-ray 1.70A ) 4IRH (X-ray 2.10A ) 4IRI (X-ray 2.77A ) 5YBC (X-ray 2.50A ) 5YBD (X-ray 2.77A ) 6VGE (X-ray 4.25A ) 6VGG (X-ray 4.31A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00237, ECO:0000269|PubMed:17289661}. Cytoplasm {ECO:0000269|PubMed:17289661}. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs. |
| Mouse PG classification | NA |
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