| Gene Information | |
|---|---|
| Gene Name | ERF3B |
| Organism | Homo sapiens (Human) |
| Gene Length | 628 |
| Protein Names | Eukaryotic peptide chain release factor GTP-binding subunit ERF3B (Eukaryotic peptide chain release factor subunit 3b) (eRF3b) (G1 to S phase transition protein 2 homolog) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q8IYD1 |
| Gene Card | GSPT2 |
| Uniprot ID | Q8IYD1 |
| Pfam | PF00009; PF03143; PF07145 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Highly expressed in IUCC stage II colorectal cancer (CRC). {ECO:0000269|PubMed:16721809}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001860(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3KUJ (X-ray 1.40A ) |
| DBSNP | rs17855593 |
| Subcellular location [CC] | Cytoplasm {ECO:0000305}. |
| Mouse PG classification | NA |
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