| Gene Information | |
|---|---|
| Gene Name | ERF |
| Organism | Homo sapiens (Human) |
| Gene Length | 548 |
| Protein Names | ETS domain-containing transcription factor ERF (Ets2 repressor factor) (PE-2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 886 ( ENSG00000105722 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P50548 |
| Gene Card | ERF |
| Uniprot ID | P50548 |
| Pfam | PF00178 |
| In ASD | no |
| Allosteric Prediction | no (-0.51981051) |
| Ortholog in Animals | Alpaca_ ERF ( ortholog_one2one ) Dog_ ERF ( ortholog_one2one ) Macaque_ ERF ( ortholog_one2one ) Mouse_ Erf ( ortholog_one2one ) Pig_ ERF ( ortholog_one2one ) Rat_ Erf ( ortholog_one2one ) Rabbit_ ERF ( ortholog_one2one ) |
| Ohnologs | ETV3 |
| Paralogs | ELK1, ETV6, ERG, ETV4, ETV7, ELF4, ELF3, EHF, ETV2, ETV3L, ETS2, FLI1, GABPA, ETV5, ETV1, ELF5, ETV3, ELK3, ETS1, ELF2, SPI1, ELK4, ELF1, SPIB, FEV, SPIC, ERFL, SPDEF |
| Tissue | NA |
| Tissue Specificity | Highest levels in testis, ovary, pancreas, and heart. {ECO:0000269|PubMed:9192842}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7JSA (X-ray 2.85A ) 7JSL (X-ray 4.51A ) |
| DBSNP | rs587777009 rs587777008 rs886041001 rs1053655 |
| Subcellular location [CC] | Nucleus. |
| Mouse PG classification | HPG |
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