| Gene Information | |
|---|---|
| Gene Name | ERD2.1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 212 |
| Protein Names | ER lumen protein-retaining receptor 1 (KDEL endoplasmic reticulum protein retention receptor 1) (KDEL receptor 1) (Putative MAPK-activating protein PM23) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P24390 |
| Gene Card | KDELR1 |
| Uniprot ID | P24390 |
| Pfam | PF00810 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Golgi apparatus membrane {ECO:0000269|PubMed:18086916, ECO:0000269|PubMed:2172835, ECO:0000269|PubMed:30846601, ECO:0000269|PubMed:8392934}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P33946}. Cytoplasmic vesicle, COPI-coated vesicle membrane {ECO:0000269|PubMed:18086916}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P33946}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:18086916, ECO:0000269|PubMed:30846601, ECO:0000269|PubMed:8392934}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P33946}. Endoplasmic reticulum-Golgi intermediate compartment membrane {ECO:0000250|UniProtKB:P33946}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P33946}. Note=Localized in the Golgi in the absence of bound proteins with the sequence motif K-D-E-L. Trafficks back to the endoplasmic reticulum together with cargo proteins containing the sequence motif K-D-E-L. {ECO:0000269|PubMed:18086916, ECO:0000269|PubMed:30846601, ECO:0000269|PubMed:8392934}. |
| Mouse PG classification | NA |
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