| Gene Information | |
|---|---|
| Gene Name | ERCC6 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1061 |
| Protein Names | Chimeric ERCC6-PGBD3 protein (Chimeric CSB-PGBD3 protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000225830 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P0DP91 |
| Gene Card | ERCC6 |
| Uniprot ID | P0DP91 |
| Pfam | PF13843 |
| In ASD | no |
| Allosteric Prediction | yes (0.362042928) |
| Ortholog in Animals | Alpaca_ ERCC6 ( ortholog_one2one ) Dog_ ERCC6 ( ortholog_one2one ) GuineaPig_ ERCC6 ( ortholog_one2one ) Macaque_ ERCC6 ( ortholog_one2one ) Mouse_ Ercc6 ( ortholog_one2one ) Rat_ Ercc6 ( ortholog_one2one ) Rabbit_ ERCC6 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SMARCA1, RAD54B, HLTF, HELLS, SHPRH, BTAF1, ZRANB3, SMARCA5, TTF2, SMARCA2, CHD9, SMARCAL1, CHD1L, CHD3, RAD54L2, SMARCAD1, CHD4, ATRX, INO80, CHD6, SRCAP, CHD1, CHD2, RAD54L, CHD7, CHD8, EP400, ERCC6L, CHD5, SMARCA4 |
| Tissue | NA |
| Tissue Specificity | Expressed in heart and oocytes, but not in granulosa cells (at protein level). {ECO:0000269|PubMed:26218421}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs4253072 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:26218421}. |
| Mouse PG classification | NA |
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