| Gene Information | |
|---|---|
| Gene Name | KCNH4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1017 |
| Protein Names | Potassium voltage-gated channel subfamily H member 4 (Brain-specific eag-like channel 2) (BEC2) (Ether-a-go-go-like potassium channel 1) (ELK channel 1) (ELK1) (Voltage-gated potassium channel subunit Kv12.3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000089558 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9UQ05 |
| Gene Card | KCNH4 |
| Uniprot ID | Q9UQ05 |
| Pfam | PF00520; PF13426 |
| In ASD | no |
| Allosteric Prediction | yes (0.001970259) |
| Ortholog in Animals | Alpaca_ KCNH4 ( ortholog_one2one ) Dog_ KCNH4 ( ortholog_one2one ) GuineaPig_ KCNH4 ( ortholog_one2one ) Macaque_ KCNH4 ( ortholog_one2one ) Mouse_ Kcnh4 ( ortholog_one2one ) Pig_ KCNH4 ( ortholog_one2one ) Rat_ Kcnh4 ( ortholog_one2one ) Rabbit_ KCNH4 ( ortholog_one2one ) |
| Ohnologs | KCNH2, KCNH3, KCNH8, KCNH7 |
| Paralogs | KCNH7, KCNH1, HCN3, CNGA3, KCNH3, HCN4, HCN2, KCNH8, HCN1, CNGB3, CNGB1, CNGA1, KCNH6, KCNH2, CNGA2, CNGA4, KCNH5 |
| Tissue | NA |
| Tissue Specificity | Detected only in brain, in particular in the telencephalon. Detected in putamen and caudate nucleus, and at lower levels in cerebral cortex, occipital and hippocampus. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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