| Gene Information | |
|---|---|
| Gene Name | ERC2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 957 |
| Protein Names | ERC protein 2 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000187672 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | O15083 |
| Gene Card | ERC2 |
| Uniprot ID | O15083 |
| Pfam | PF10174 |
| In ASD | no |
| Allosteric Prediction | no (-0.919355568) |
| Ortholog in Animals | Alpaca_ ERC2 ( ortholog_one2one ) Dog_ ERC2 ( ortholog_one2one ) GuineaPig_ ERC2 ( ortholog_one2one ) Macaque_ ERC2 ( ortholog_one2one ) Mouse_ Erc2 ( ortholog_one2one ) Pig_ ERC2 ( ortholog_one2one ) Rat_ Erc2 ( ortholog_one2one ) Rabbit_ ERC2 ( ortholog_one2one ) |
| Ohnologs | ERC1 |
| Paralogs | ERC1 |
| Tissue | brain, cerebral.cortex |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs12488237 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:12923177}. Synapse {ECO:0000269|PubMed:12923177}. Presynaptic active zone {ECO:0000269|PubMed:12923177}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:12923177}. Note=In neurons, localized to synapses, and colocalizes with PCLO. Localized to the active zone of presynaptic density (By similarity). {ECO:0000250}. |
| Mouse PG classification | NA |
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