| Gene Information | |
|---|---|
| Gene Name | UBE2A |
| Organism | Homo sapiens (Human) |
| Gene Length | 152 |
| Protein Names | Ubiquitin-conjugating enzyme E2 A (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme A) (RAD6 homolog A) (HR6A) (hHR6A) (Ubiquitin carrier protein A) (Ubiquitin-protein ligase A) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000077721 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P49459 |
| Gene Card | UBE2A |
| Uniprot ID | P49459 |
| Pfam | PF00179 |
| In ASD | no |
| Allosteric Prediction | yes (0.053769446) |
| Ortholog in Animals | Alpaca_ UBE2A ( ortholog_one2one ) Dog_ UBE2A ( ortholog_one2many ) Macaque_ UBE2A ( ortholog_one2one ) Mouse_ Ube2a ( ortholog_one2one ) Pig_ UBE2A ( ortholog_one2one ) Rat_ Ube2a ( ortholog_one2one ) |
| Ohnologs | UBE2B |
| Paralogs | UBE2T, UBE2B, UBE2O, UBE2J2, UBE2C, UBE2H, UBE2V1, UBE2K, UBE2W, UBE2Z, UBE2F, UBE2G2, UBE2I, UBE2V2, UBE2N, UBE2NL, PEDS1, UBE2U, UBE2J1, UBE2G1, UBE2S, CDC34, UBE2R2, AKTIP |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.015789(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6CYO (X-ray 1.85A ) 6CYR (X-ray 2.20A ) |
| DBSNP | rs387906728 rs1556235551 |
| Subcellular location [CC] | NA |
| Mouse PG classification | LPG |
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