| Gene Information | |
|---|---|
| Gene Name | EPX |
| Organism | Homo sapiens (Human) |
| Gene Length | 715 |
| Protein Names | Eosinophil peroxidase (EPO) (EC 1.11.1.7) [Cleaved into: Eosinophil peroxidase light chain; Eosinophil peroxidase heavy chain] |
| Target Name | eosinophil peroxidase |
| Target Type | NA |
| Gene Age | 1064 ( ENSG00000121053 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P11678 |
| Gene Card | EPX |
| Uniprot ID | P11678 |
| Pfam | PF03098 |
| In ASD | no |
| Allosteric Prediction | yes (0.642932046) |
| Ortholog in Animals | Alpaca_ EPX ( ortholog_one2one ) Dog_ EPX ( ortholog_one2one ) GuineaPig_ EPX ( ortholog_one2one ) Macaque_ EPX ( ortholog_one2one ) Mouse_ Epx ( ortholog_one2one ) Pig_ EPX ( ortholog_one2one ) Rat_ Epx ( ortholog_one2one ) Rabbit_ EPX ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PXDNL, PXDN, TPO, LPO, MPO |
| Tissue | bone.marrow |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs34553736 rs11079339 rs11652709 rs35896669 rs35074452 rs121434566 rs33971258 rs35832094 rs35832094 rs35135976 rs35232062 rs35750729 rs34817773 rs33955150 rs2302311 |
| Subcellular location [CC] | Cytoplasmic granule. Note=Cytoplasmic granules of eosinophils. |
| Mouse PG classification | NA |
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